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Film Appearances
- The Kid from Spain (1932)
- Elmer, the Great (1933)
- College Rhythm (1934)
- All the King's Horses (1935)
- Rumba (1935)
- George White's 1935 Scandals (1935)
- Stolen Harmony (1935)
- King of Burlesque (1936) †
- Anything Goes (1936)
- The Sunday Round-Up (1936) (short subject)
- My Man Godfrey (1936)
- Stage Struck (1936)
- Cain and Mabel (1936)
- Here Comes Carter (1936)
- Polo Joe (1936)
- Gold Diggers of 1937 (1936)
- Smart Blonde (1937)
- Ready, Willing and Able (1937)
- The King and the Chorus Girl (1937)
- Slim (1937)
- The Singing Marine (1937)
- Public Wedding (1937)
- Little Pioneer (1937) (short subject)
- Mr. Dodd Takes the Air (1937)
- Over the Goal (1937)
- The Spy Ring (1938)
- He Couldn't Say No (1938)
- Fools for Scandal (1938)
- Wide Open Faces (1938)
- The Crowd Roars (1938)
- Brother Rat (1938) †
- Tail Spin (1939)
- The Kid from Kokomo (1939)
- Torchy Blane... Playing with Dynamite (1939)
- Kid Nightingale (1939)
- Private Detective (1939)
- Brother Rat and a Baby (1940)
- An Angel from Texas (1940)
- Flight Angels (1940)
- My Love Came Back (1940)
- Gambling on the High Seas (1940)
- Tugboat Annie Sails Again (1940)
- Honeymoon for Three (1941)
- Bad Men of Missouri (1941)
- You're in the Army Now (1941) †
- The Body Disappears (1941) †
- Sports Parade: Shoot Yourself Some Golf (1942) (short subject)
- Larceny, Inc. (1942)
- My Favorite Spy (1942)
- Footlight Serenade (1942)
- Princess O'Rourke (1943)
- Make Your Own Bed (1944)
- The Doughgirls (1944)
- Crime by Night (1944)
- Hollywood Canteen (1944)
- The Lost Weekend (1945) †
- One More Tomorrow (1946)
- Night and Day (1946)
- The Yearling (1946) † [Oscar nomination - Best Actress]
- Cheyenne (1947)
- Magic Town (1947) †
- Johnny Belinda (1948) † [Oscar & Golden Globe Winner - Best Actress]
- A Kiss in the Dark (1949) †
- It's a Great Feeling (1949) † (cameo)
- The Lady Takes a Sailor (1949)
- Stage Fright (1950) †
- The Glass Menagerie (1950) †
- Three Guys Named Mike (1951)
- The Screen Director (1951) (short subject)
- Screen Snapshots: Hollywood Awards (1951) (short subject)
- Here Comes the Groom (1951) †
- The Blue Veil (1951) † [Oscar nomination/Golden Globe winner - Best Actress]
- Starlift (1951) (cameo)
- The Story of Will Rogers (1952)
- Just for You (1952) †
- Three Lives (1953) (short subject)
- Let's Do It Again (1953)
- So Big (1953)
- Magnificent Obsession (1954) † [Oscar nomination - Best Actress]
- Hollywood Mothers and Fathers (1955) (short subject)
- Lucy Gallant (1955)
- All That Heaven Allows (1955) †
- Miracle in the Rain (1956)
- Holiday for Lovers (1959)
- Pollyanna (1960) †
- Bon Voyage! (1962)
- How to Commit Marriage (1969) †
- Wild Bill: Hollywood Maverick (1996) (documentary)
- Off the Menu: The Last Days of Chasen's (1997) (documentary)
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Television Appearances
Major Appearances in Bold. Series titles in italics.
- General Electric Theater
• Amelia (1955) Dr. Amelia Morrow
- The Bamboo Cross
• (1955) Sister Regina
- Jane Wyman Presents The Fireside Theatre (a.k.a. Jane Wyman Theatre)
• Host & producer (49 episodes, 1955 - 1958)
- Summer Playhouse
• (1957) Host
- Lux Playhouse
• A Deadly Guest (1959) Selena Shelby
- Westinghouse Desilu Playhouse
• Dr. Kate (1960) Dr. Kate
- Checkmate
• Lady on the Brink (1960) Joan Talmadge
- The Investigators
• Death Leaves a Tip (1961) Elaine
- Wagon Train
• The Doctor Willoughby Story (1958) Dr. Carol Willoughby
• The Wagon Train Mutiny (1962) Hannah
- The Bell Telephone Hour
• The Younger Generation (1964) Hostess
- Bob Hope Presents the Chrysler Theatre
• When Hell Froze (1966) † Addie Joslin
- Insight
• Why Does God Allow Men to Suffer? (1967) Marie
• The Hermit (1970) Marie
- The Failing of Raymond
• (1971) Mary Bloomquist
- The Sixth Sense
• If I Should Die Before I Wake (1972) Ruth Ames
- The Bold Ones: The New Doctors
• Discovery at Fourteen (1972) † Dr. Amanda Fallon
• And Other Things I May Not See (1973) Dr. Amanda Fallon
- Amanda Fallon
• Unsold Pilot (1973) Dr. Amanda Fallon
- Owen Marshall: Counselor at Law
• The Desertion of Keith Ryder (1974) Sophia Ryder
- The Incredible Journey of Doctor Meg Laure
• (1979) Granny Arrowroot
- The Love Boat (1980)
• Another Time, Another Place/Doctor Who/Gopher's Engagement (1980) Sister Patricia
- Charlie's Angels
• To See an Angel Die (1980) Eleanor Willard
- Falcon Crest † [Golden Globe Winner - Best Actress 1984]
• Angela Channing (212 episodes, 1981-1990)
- Dr. Quinn, Medicine Woman
• The Visitor (1993) Elizabeth Quinn
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